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10.1038/npp.2017.150 Neuropsychopharmacology 54 PoesselM.BreuerN.JoshiA.PampelA.VillringerA.HummelT.et al (2020)
Cyclic AMP promotes growth and secretion in human polycystic kidney epithelial cells
Qualifying criteria include BMI greater than 27 with prediabetes or established cardiovascular disease, or BMI over 30 with uncontrolled hypertension, advanced kidney disease, or heart failure
Nutritional strategies form the foundation of craving management: Include adequate protein at each meal (often 20-30g per meal is helpful), as protein promotes satiety and helps stabilise blood glucose levels, reducing the likelihood of sugar cravings Choose complex carbohydrates such as wholegrain bread, brown rice, oats, and pulses, which provide sustained energy release and prevent the blood sugar fluctuations that can trigger sweet cravings Don't restrict calories too severely Wegovy already reduces appetite, so additional extreme restriction may backfire by intensifying cravings Stay well hydrated , as thirst is sometimes misinterpreted as hunger or cravings
