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The sensation of coldness appears more closely linked to the metabolic and physical changes accompanying weight reduction

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PMCID: PMC4966972

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Work by Goldstein and colleagues, who first characterised the thymosin family of peptides, established thymosin beta-4 as a major actin-sequestering protein with roles in wound healing and anti-inflammatory signalling

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The theory is that boosting HGH levels could help counter some of the changes that often accompany midlife, from increasing belly fat (hello, meno belly) to declining muscle mass and lower energy levels (hello, 3am club)

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