La vida media biolgica del GLP-1 in vivo es corta (aproximadamente 2 minutos) y se degrada rpidamente por la accin de la enzima dipeptidil dipeptidasa-4 (DPP-4)21, por tanto, el enfoque farmacolgico ha sido dirigido a prolongar la vida media del GLP-1, ya sea por modificacin estructural del pptido original o por inhibicin de la enzima DDP-4
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When you eat 1,200-1,600 calories instead of 2,000-2,500, you get proportionally fewer vitamins and minerals
It was found a significant decrease in lymphohistiocytic infiltration in the gastric mucosa, restoration of the structure of the pancreas, and increased focal proliferation of the glandular epithelium which were considered as the signs of morphological restoration of the epithelium and reduction of the signs of its dysplasia