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Pomalidomide, the third-generation IMiD following thalidomide and lenalidomide, has recently been employed in a PROteolysis TArgeting Chimera (PROTAC) strategy

Molecular drivers of epithelial-mesenchymal transition (EMT) in glioblastoma and impact on therapy resistance

Mechanism of Action: Selective muscarinic agonist, resistant to hydrolysis by different cholinesterase isoenzymes The same backbone structure as acetylcholine, but with a methyl side group (Figure 1), which is responsible for its selectivity for muscarinic vs nicotinic receptors (Vardanyan & Hruby, 2006)

Detoxification is especially important when it comes to removing heavy metals like mercury, which can linger in brain tissue and contribute to neurological disorders