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A B12 shot takes roughly 5 to 10 minutes, including preparation and the injection itself

In some embodiments, a trophic effect is desirable during otic surgery or during intratympanic injection procedures

Given the concentration of SHBG increases across the lifespan in men (Liu et al., 2007) and only increase after ~60 y in women (Maggio et al., 2008), bioavailable testosterone (free plus albumin-bound testosterone) concentrations decline even more markedly than total testosterone levels with aging (Matsumoto, 2002)