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Another trial did not find creatine monohydrate to be efficacious compared to placebo in treating bipolar depression, but creatine monohydrate performed better than placebo when remission criteria were considered [65]

New perspectives on the involvement of mtor in depression as well as in the action of antidepressant drugs

OHarte, Ulster University, United Kingdom

Ideal candidates typically include adults with type 2 diabetes who have inadequate glycaemic control (HbA1c above individualised target) despite treatment with metformin and/or other oral agents, particularly those with additional cardiovascular or renal risk factors