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[15] For patients undergoing significant dietary restriction as may occur with retatrutide guidance from the British Obesity and Metabolic Surgery Society (BOMSS) on post-bariatric nutritional monitoring offers a useful parallel, recommending routine monitoring of B12, iron, folate, and vitamin D

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This indicates that patients may still experience the appetite regulation benefits of GLP-1s, even at lower doses, and the effects may be more gradual and gentler, which could be beneficial for long-term adherence