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Most patients tolerate tirzepatide very well, but some may experience nausea, constipation, bloating, or fatigue during the first few weeks

Flow cytometry also demonstrated greater SRY-box transcription factor 2 ( SOX2 ) expression, a gene involved in regulation of cell proliferation, in hMSC when treated with Ex-4 [15]

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Researchers comparing KLOW protocols may use four weeks as a useful reference point, but PDP does not recommend it as a personal protocol