If you find that a morning dose makes you want to nap by noon, switching to a nighttime administration can help you use that fatigue to your advantage for a better nights sleep
Br J Pharmacol 2016;173:6676 [DOI] [PMC free article] [PubMed] [Google Scholar] 85.Bateman DN, Dear JW, Thanacoody HK, Thomas SH, Eddleston M, Sandilands EA, Coyle J, Cooper JG, Rodriguez A, Butcher I, Lewis SC, Vliegenthart AD, Veiraiah A, Webb DJ, Gray A.Reduction of adverse effects from intravenous acetylcysteine treatment for paracetamol poisoning: a randomised controlled trial
Most side effects are manageable, especially with gradual titration
Painful diabetic peripheral neuropathy: practical guidance and challenges for clinical management