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Benzotriazole is antiestrogenic in vitro but not in vivo

Efficacy and safety of mirogabalin (DS-5565) for the treatment of diabetic peripheral neuropathic pain: a randomized, double-blind, placebo- and active comparator-controlled, adaptive proof-of-concept phase 2 study

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According to the SmPC, you should take it on the same day each week, though the day can be changed if necessary as long as the last dose was given at least 3 days earlier