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In this direction we additionally observed metabolic changes to prevent the production of ROS: (i) downregulation of the tricarboxylic acid (TCA) cycle ( BC1251*, BC3833*, BC3834*, BC1790*, BC0466*, BC1712*, BC0466 *), including Complex II of the electron transport chain (BC4516*, BC4517*), which supplies two electrons to ubiquinone (Fig

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