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Most of the brain targeting agents were developed based on a receptor- or carrier-mediated endocytosis process at the BBB

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[Google Scholar] The yeast Eif2 kinase Gcn 2 facilitates H 2 O 2 -mediated feedback inhibition of both protein synthesis and endoplasmic reticulum oxidative folding during recombinant protein production

Thus, to enhance SOD activity in S-3, we selected sod -lc for heterologous expression using our previous constructed native constitutive promoter library (Supplementary Table 1