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Last but not least, given the recency of these prescribing trends, no long-term data on the next-generation effects of these medications is available, leading to several uncertainties about the possibility and implications of long-term use

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Not saying this is going to work the same for everyone, but for my situation it made a real difference

Diarrhea, vomiting and other side effects of Zepbound and Mounjaro can cause severe dehydration, leading to acute kidney injury (AKI)