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CCI, chronic constriction injury

FIGURE 3 Another notable finding revealed by PET and NMR (nuclear magnetic resonance) spectroscopy analysis, is that in the brains of patients affected by ASD were found decreased glucose utilization and reduced ATP levels, further confirming mitochondrial dysfunction (Palmieri and Persico, 2010)

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As many cysteine-containing proteins (transporters, receptors and enzymes) at extracellular surfaces or in extracellular fluids are prone to oxidation, their activity might be influenced by the thiol/disulphide redox microenvironment