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J Clin Epidemiol 121:8190
Generally, it takes at least 12-17 weeks to reach the maximum tolerated and fully effective dose after switching to a new medication
Body composition analyses from clinical studies indicate that a portion of weight lost may be lean mass rather than fat mass
Several important safety considerations from the SmPC should be noted: If pancreatitis is suspected, Ozempic should be discontinued immediately and urgent medical assessment sought Patients should be counselled about gallbladder disease symptoms, as GLP-1 receptor agonists may increase the risk of gallstones [14] Those with pre-existing diabetic retinopathy should be monitored for potential worsening, particularly during rapid improvement in glucose control If a patient is taking warfarin or other coumarin derivatives, more frequent INR monitoring is recommended when starting Ozempic [1] Before initiating Ozempic in patients with known liver conditions, healthcare professionals should conduct a thorough assessment of liver disease severity, review concurrent medications for potential interactions, and establish baseline liver function tests
