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These alternatives each have their own availability challenges and compounding considerations, but understanding the full landscape helps researchers make informed decisions about which GLP-1 approach best fits their needs

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Scaffidi, P., Misteli, T

This was the first study suggesting a disturbance of glutamatergic transmission in RLS, and suggesting the mechanisms of action of glutamatergic drugs (that is, 2 ligands) and other arousal-reducing agents