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82405266), Natural Science Foundation of Jiangsu Province of China (BK20230447), Jiangsu Traditional Chinese Medicine Science and Technology Development Project (QN202202), Jiangsu Province of Youth Science and Technology Talent Nurturing Project (JSTJ-2024-452), NATCMs Project of High-level Construction of Key TCM Disciplines (GSPZDXK-FJXYB018), Luo LinXiu Teacher Development Fund Project (LLX202312), Nanjing University of Traditional Chinese Medicine College Student Innovation Training Program Plan (202410315059Z), Nanjing University of Traditional Chinese Medicine College Student Innovation Training Program Plan (202310315111Y), Jiangsu province Graduate Research and Practice Innovation Program (CX10315)
PLoS One 10 (6), e0127551
the build-up of oxidised glutathione dimers (GSSG) causes membrane damage and haemolysis
While dedicated Phase III clinical trials for GHK-Cu hair loss are absent, the compound's human clinical evidence for adjacent applications is meaningful: randomized trials for skin rejuvenation demonstrated statistically significant collagen production increases, and clinical wound healing studies showed accelerated re-epithelialization
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