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Thyroid diseases are the most common endocrine system disorders, affecting an estimated 5% of the US population, with Graves disease and Hashimotos thyroiditis accounting for a vast majority of cases. , Despite their prevalence, the underlying causes of thyroid autoimmunity remain complex and multifactorial, evolving over time and involving a perfect storm of risk factors: a genetic predisposition, environmental triggers, and an imbalanced immune system

People with a history of cancer should be particularly wary, as IGF-1 (which increases with CJC-1295) may be involved in the development of certain types of cancer

Severe Graves disease in a child following a single dose of Pfizer-BioNTech SARS-CoV-2 vaccine

Brush at least 30 minutes before dosing