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This 60% reduction coincides with observable decreases in regenerative capacity, wound healing efficiency, and overall tissue maintenance

Lysine Attachment Chemistry The covalent attachment occurs through the -amino group of the lysine residue at position 17, utilizing established peptide conjugation chemistry that provides stable, reproducible linkage [16] [12]

Furthermore, we find that the addition of sulfite to these reactions strongly inhibits the O 2 consumption, presumably via competition for docking at the positive patch with S -sulfonated C201 (Fig