10.1002/jat.3499 204 WuW.HeQ.JiangC
The BBB employs various transport systems, such as carrier-mediated transport (CMT), receptor-mediated transport (RMT), active efflux transport, vesicular trafficking by transcytosis, and ion transport, to facilitate the entry of essential substances into the brain parenchyma and the efflux of metabolic waste and endogenous neurotoxins [19, 23]
Clinical guidelines recommend standard protocols of 100 mcg IM/SC once daily for 6-7 days, then every other day for 7 doses, then every 3-4 days for 2-3 weeks, then monthly, but these protocols dont even mention that injection site makes a huge difference in how well those doses actually work
Weve also seen that many of our clients on GLP-1s feel more alert and focused when they receive B12 regularly