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Elevated GH and IGF-1 promote metabolic health, trim fat, and develop lean muscle

Before starting, patients should undergo baseline bloodwork including oxidative stress markers, liver and kidney function, inflammatory cytokines, and ideally genetic assessment in glutathione metabolism pathways

Because the body spews free radicals when it uses oxygen, the brain is awash in rogue molecules

Notably, administration of Fer-1 or overexpression of SIRT7 effectively alleviated Ang II-induced epithelial-mesenchymal transition (EMT) and renal ferroptosis in hypertensive mice by suppressing the KIM-1/NOX4 signaling pathway and activating the KLF15/NRF2 and xCT/GPX4 signaling pathways, respectively [263]