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PMID 11665618

Targeting PI3K pathway with Copanlisib along with ADT reduces lactate secretion and, thus, tumor growth repression helped by immunosuppression of activated TAMs in a PTEN/p53-deficient murine PC model [140]

speaker/consultation fees from Lundbeck, Janssen, Alkermes, Neumora Therapeutics, Boehringer Ingelheim, Sage, Biogen, Mitsubishi Tanabe, Purdue, Pfizer, Otsuka, Takeda, Neurocrine, Sunovion, Bausch Health, Axsome, Novo Nordisk, Kris, Sanofi, Eisai, Intra-Cellular, NewBridge Pharmaceuticals, Viatris, Abbvie, Atai Life Sciences

Once removed from shortage status, compounding becomes more legally precarious, potentially reducing availability and increasing costs