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Cervical or lumbar radiculopathy from spinal nerve root compression can cause dermatomal numbness and may be exacerbated by obesity

Many patients choose tirzepatide specifically because they experience better results, appreciate the weekly dosing schedule, and often find they tolerate it well despite the higher initial likelihood of side effects

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Dietary habits and meal composition also influence symptom durationhigh-fat, large-volume meals tend to exacerbate and prolong gastrointestinal side effects