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10.1093/ajcn/80.6.1611 Am

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Metabolic Stability More consistent drug levels could provide: Steady appetite suppression: Avoiding the "feast-famine" cycle of weekly dosing Consistent energy levels: Reduced fluctuation in metabolic rate Better glucose control: Continuous incretin effect rather than peaks and valleys Improved sleep: Less variation in nocturnal glucose and hunger hormones 3

Methods Culture conditions Three strains of anaerobic bacteria, isolated by culturomics studies 21,22,23 and obtained from the Collection de Souches de lUnit des Rickettsies (CSUR, Marseille, France), were used for this study: Clostridium sporogenes CSURP3957, Clostridium subterminale CSURP3759 and Romboutsia lituseburensis CSURP3909