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TB-500 is commonly studied in research settings for its role in actin-related cellular processes, peptide-mediated signaling, and molecular pathways involved in cell migration and structural regulation

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PNPLA3 can remodel the phospholipid monolayer in LDs (79) by transferring polyunsaturated FAs from TAG to phospholipids via transacylation, or possibly through TAG hydrolase activity (80) and can promote FA re-esterification during lipolysis possibly through lysophosphatidic acid acyltransferase (LPAAT) or transacylase activity (70)