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Mitochondrial-derived reactive oxygen species and oxidized mtDNA are potent activators of the NLRP3 inflammasome, driving maturation of IL-1 and IL-18, which in turn enhance Th1 and Th17 responses essential for protection against Candida albicans and Aspergillus fumigatus (Patel et al., 2018)

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Patellar Tendonitis Symptoms, Causes & Treatment Overcome Tendon Pain & Restore Strength Patellar tendonitis, commonly known as jumpers knee, is a frustrating and often persistent condition impacting athletes, fitness enthusiasts, and anyone whose activities demand repetitive jumping or knee extension