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When those systems get stressed, natural peptide output declines, which is why adults often feel like their recovery switch is broken
The GST domain is also found in S-crystallins from squid, and proteins with no known GST activity, such as eukaryotic elongation factors 1-gamma and the HSP26 family of stress-related proteins, which include auxin-regulated proteins in plants and stringent starvation proteins in Escherichia coli
J Pers Med 14(1):126
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