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Studies using the Caco-2 Brush Border Expressing clone 1 cell line (Caco-2 BBe1) model demonstrate that glycosylated flavonoids are primarily absorbed via Sodium-dependent glucose transporter 1- and Glucose transporter 2-mediated active transport, whereas aglycones are mainly taken up by passive diffusion (Zhang et al., 2020)

In the IFIGENIA study, adding NAC 600 mg/day to prednisone and azathioprine slowed lung function decline and improved Diffusing Capacity of the Lung for Carbon Monoxide (DLCO), especially in early IPF (136, 137)

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