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There is no evidence that semaglutide directly reduces the effectiveness of the oral contraceptive pill, though its important to be aware that some side effects could impact the effectiveness of your pill

According to a 2017 systematic review in the Journal of Clinical Nursing confirming that aspiration before subcutaneous injection does not reduce adverse events, subcutaneous injections carry a distinct pharmacokinetic profile that intramuscular delivery disrupts, which is why correct angle and depth matter for predictable results