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In a multicenter open-label randomized controlled trial, exenatide alone or in combination with basal insulin showed to be safe and effective for the management of hyperglycemia when compared with basal-bolus insulin regimen in 150 hospitalized general medical and surgical patients with type 2 diabetes

Often, a combined approach yields the most effective results

It does not account for the reality of most research or home-use scenarios: vials stored in drawers at ambient temperature, needles reinserted without alcohol swabbing the stopper, and reconstitution performed on non-sterile surfaces

In terms of spindle assembly, oxidative stress damages the microtubule-organizing center (MTOC) by altering proteins like CCP110 and TACC3