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Mol Cell Proteom 6:20582071 Desai KM, Chang T, Wang H, Banigesh A, Dhar A, Liu J, Untereiner A, Wu L (2010) Oxidative stress and aging: Is methylglyoxal the hidden enemy

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Therefore, while the circulating methionine levels were higher in MSD mice, apical transport of methionine could be impaired by rapid passage of methionine from the gut lumen into the blood stream via paracellular transport (facilitated by the nonfunctional tight junctions)