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93 In contrast, markers of mineral metabolismincluding 25-hydroxyvitamin D, bone-specific alkaline phosphatase (BALP), and PTHremain largely stable over the long term, 94 suggesting that VSG-mediated skeletal remodeling occurs independently of traditional calciumphosphorus regulatory pathways

Ironically, many women with PCOS report improved energy over time on tirzepatide

The indirect causes, glycogen depletion, dietary changes, blood sugar normalization, are also shared across medications that produce significant weight loss and metabolic improvement