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Key gap: no human trial has been published, and no human pharmacokinetic study is widely available
During chronic sleep restriction, high nitrogen stress leads to induction of both NO and polyamine synthesis that likely serve together to promote sleep, helping to behaviorally reduce nitrogen stress and head off neurotoxicity (Gautier-Sauvign et al., 2005
It is often described in scientific literature as a stable gastric pentadecapeptide, with the amino acid sequence GEPPPGKPADDAGLV and a molecular weight of approximately 1419 Da
It helps make myelin, the fatty layer that protects nerves
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