Arlinking Ong-Go, Personal communication (interview), April 13, 2023 Philippine Society of Gastroenterology, Mission and Vision, Accessed April 13, 2023 Philippine Food and Drug Administration, Nekothione, Nov
There is only the case of the nuclear transcription factor c-Jun that, due to an unusual redox potential, could react with GSSG at relatively high ratio of GSH/GSSG = 13 ( S -glutathionylation within the cells involves reaction of the critical cysteine on protein or GSH with a corresponding oxidized derivative such as S-nitrosyl ( S -NO), sulfenic acid ( S -OH), thiyl radical ( S )
8 In contrast, the presence of glutathione and its disulfide in the plasma has been suggested based on the detection of thiol group using Ellmans reagent and glutathione reductase
34 Intriguingly, researchers have provided further evidence to demonstrate that NBDHEX can also act as an autophagy inhibitor in tumor cells