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Confirmatory diagnostic studies should be performed prior to initiating therapy, if possible, and the patient should be followed with appropriate studies to demonstrate hematologic improvement (Hgb, hematocrit, RBC, reticulocyte count)

The frequent reliance on multidrug treatment strategies highlights the limited understanding of ASD pathophysiology and is based on the limited efficacy of currently available pharmacological therapies

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In the placebo group, patients who had a complication lost an average of 3.3 kg compared with 0.6 kg in those who did not have a complication