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7 Conclusion The influence of the gut microbiota and metabolites in the gut-brain-kidney axis, especially in relation to CKD, is a novel research area currently gaining increasing interest among researchers of renal health and the gut microbiome

doi: 10.3390/IJMS150916153 24 BrosnanJ.BrosnanM.BertoloR.BruntonJ

However, in cases of gut microbiome imbalance, retina-specific T cells can become activated, entering the peripheral circulation and potentially inducing inflammation through the BRB (102)