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Figure 2: Novel Incretin Mimetic Assets for T2DM and Obesity in Phase 2/3 of Development Remaining Unmet Needs Remaining Unmet Needs Though the value proposition of on-market GLP-1 and dual-agonists is strong, several key unmet needs still exist for incretin mimetics across diabetes and obesity, namely: (1) improved efficacy, (2) better tolerability, (3) more convenient options / alternative ROAs, and (4) improved access and affordability

Heres a closer look at the most common reasons GLP-1s are prescribed: Type 2 diabetes GLP-1s were first approved as diabetes medications because of how effectively they lower blood sugar

Higham CS, Steinberg SM, Dombi E, Perry A, Helman LJ, Schuetze SM, et al

Patients should feel confident and supported in their ability to manage weight and health without relying solely on medication