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The primary outcomes of the study were changes in HbA1c, body weight, and FPG from baseline, while safety outcomes were selected as secondary outcomes

Highlights The starting tirzepatide dosage for weight management is low (2.5 mg weekly) and is increased slowly (by 2.5 mg weekly after at least 4 weeks) because side effects are common but usually temporary and manageable

It has also been approved by the United States Food and Drug Administration (FDA) as a medication to treat primary and certain secondary carnitine deficiency symptoms