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It has been previously reported that DNA methylation plays a role in the regulation of biofilm formation in various bacteria like (i) Salmonella enterica , where DNA adenine methyltransferase (Dam) modulates the length of O-anitgen chain of Lipopolysaccharide (LPS) by either directly regulating Wzzst production or influencing RcsB and PmrA protein expression, which subsequently alters LPS structure and affects biofilm development 7,8

Following its attachment, the SARS-CoV-2 spike protein is further cleaved to facilitate its entry into the host cell

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