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Studer, U

Functional genomics For instance, CRISPR screens in the PINK1-Parkin mitophagy pathway have identified novel cofactors and signaling partners, expanding our understanding of mitochondrial quality control and offering promising therapeutic entry points in disorders such as Parkinsons disease

[DOI] [PMC free article] [PubMed] [Google Scholar] Dwarakanath S

Head and neck cancer (HNC) In studies of HNC, two GPX 4 inhibitors, (1s, 3R)-RSL 3 and ML-162, were found to induce ferroptosis in HNC cells to varying degrees