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An average change in knee pain, assessed using the WOMAC criteria for pain scoring, showed a reduction of 41.7 points for semaglutide versus a 27.5-point decrease for a placebo

Biochem Pharmacol (2020) 175:113888

usually mild) Fishy body odor (due to trimethylamine production) Headache (occasional) Increased appetite (some patients) When to Contact Healthcare Provider: Severe GI symptoms Signs of allergic reaction (rash, swelling) Increased seizure frequency (if history of epilepsy) Unusual bleeding or bruising (if on warfarin) Symptoms of hypothyroidism (fatigue, weight gain, cold intolerance) Drug and Supplement Interactions: Warfarin: May increase anticoagulant effect

Compounded semaglutide is not going away