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Why Exercise Matters During GLP-1 Therapy Weight loss from any intervention, whether from medication, dietary changes, or surgery, involves losing both fat mass and lean muscle mass

A systematic review of multiple studies shows that weight regain is a common outcome

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The mechanism of action of the DPP-4 inhibitors raises the question: Will these agents be effective in patients who have had diabetes for 10 to 15 years and who may no longer have any beta-cell function