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Unlike small-molecule drugs (like tablets), peptide-based medicines like retatrutide work by binding to specific hormone receptors and activating them, which is why they need to be given by injection rather than taken orally

Pfizers $4.9 B acquisition of Metsera (2025) secures MET-097i and a next-gen obesity pipeline, positioning Pfizer as a major re-entrant in metabolic disease innovation