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The fact that there is no upregulation with the control treatment is probably due to the lack of metabolically available selenium

FEMS Yeast Res 2:295305 Ray S, Watkins DN, Misso NL, Thompson PJ (2002) Oxidant stress induces gamma-glutamylcysteine synthetase and glutathione synthesis in human bronchial epithelial NCI-H292 cells

The treatment plan was explained in detail, tailored to my skin needs, and the progress is constantly monitored, which shows how invested the doctor and her team is in the patients well-being