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Noting she was advised to take one shot of the lowest dose of a synthetic GLP-1, Mayim wrote in an essay for The Free Press titled My GLP-1 Nightmare published June 5 that she experienced explosive, uncontrollable diarrhea

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You want to avoid spraying directly onto the nasal septum (the cartilage dividing your nostrils), as this can cause irritation and is less effective for absorption

Instruct patients to seek medical advice if blisters or erosions occur [see Warnings and Precautions (5.6)]