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Product Overview 5-Amino-1-methylquinolinium (5-Amino-1MQ) is a small molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme involved in NAD+ metabolism and cellular energy regulation

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For example, pharmaceuticals such as ETX001 ( ACT or F ACT (Namkung et al., 2011) which would increase the activity of TMEM16A, subsequently increasing chloride and bicarbonate transport to propel water into mucus, or decrease the activity of ENaC, reducing sodium transport intracellularly and increasing water retained in mucus, could be very beneficial but are still far from public use (Livraghi-Butrico et al., 2013