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According to a 2021 assessment of 1,239 individuals with type 2 diabetes

5-MTHF is the biologically active form of vitamin B9, meaning it does not require conversion by the MTHFR enzyme, a genetic bottleneck for many individuals

So if you can preserve the muscle mass, of course that might increase functionality, but it could also have health benefits in terms of improving insulin sensitivity since muscle is the major tissue that accounts for insulin-mediated glucose uptake, and also it increases energy expenditure because of the muscle mass