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(2) It is engineered to favor growth hormone release rather than opioid activity, apparently by targeting ghrelin (growth hormone secretagogue) receptors instead of classical opioid receptors

A big win for Wegovy: Weight loss drug semaglutide first in history to gain FDA approval for reducing heart risks Semaglutide, a GLP-1 receptor agonist from Novo Nordisk, originally developed to treat diabetes, has been approved by the U.S