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Importantly, the effects of BSO and BzATP were not additive (1,334 54 neurons/mm 2 ), suggesting either that BSO and BzATP drive neuron death through the same pathways or that they act through different neurotoxic mechanisms in the same subpopulation of neurons

Methionine is not only required for cysteine de novo synthesis in the TSP but also for DNA methylation, where S- adenosylmethionine (SAM) acts as important methyl group donor for DNA methyltransferases (Figure 25A) [98]

I dont see why one would take the path of a proper drug approval if there is now this less rigorous, alternative path to market, he said

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