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The researchers discovered that small-molecule GLP-1 drugs significantly reduced how much dopamine, a neurotransmitter thats commonly associated with reward-motivated behaviors, was released, essentially changing the animals perception of how rewarding that food is. Gler hopes that his teams discovery can help guide future efforts in designing GLP-1 drugs that target specific parts of the brain, such as the reward center

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Note that if you have heart failure or kidney disease, you should follow your healthcare provider's specific advice about fluid intake

GLP-1 medications have also been associated with: Worsening of diabetic retinopathy Exacerbation of age-related macular degeneration Optic nerve complications, including NAION These risks dont mean you should stop taking your medication, but they do show why its important to have an eye exam before starting and regular follow-up exams while on treatment